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Article

hiPSC-derived hepatocytes closely mimic the lipid profile of primary hepatocytes: A future personalised cell model for studying the lipid metabolism of the liver.

Journal of cellular physiology - 1 Apr 2019

Kiamehr Mostafa, Alexanova Anna, Viiri Leena E, Heiskanen Laura, Vihervaara Terhi, Kauhanen Dimple, Ekroos Kim, Laaksonen Reijo, Käkelä Reijo, Aalto-Setälä Katriina

Abstract excerpt

Hepatocyte-like cells (HLCs) differentiated from human-induced pluripotent stem cells offer an alternative platform to primary human hepatocytes (PHHs) for studying the lipid metabolism of the liver. However, despite their great potential, the lipid profile of HLCs has not yet been characterized. Here, we comprehensively studied the lipid profile and fatty acid (FA) metabolism of HLCs and compared them with the...

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Identifiers

PMID: 30146765
DOI: 10.1002/jcp.27131

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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