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Article

Animal models of fetal growth restriction: Considerations for translational medicine

12 Mar 2015

Abstract excerpt

Fetal growth restriction (FGR) is the failure of a fetus to reach its full genetic growth potential. It occurs in up to 8% of pregnancies, and after premature birth is the second leading cause of infant mortality and morbidity. There is no treatment currently available for FGR. Its primary cause, when not attributable to structural or genetic defects of the fetus, is 'placental insufficiency'. This broad...

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PMID: 25819810
DOI: 10.1016/j.placenta.2015.03.003

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