Article

An atlas of lamina-associated chromatin across twelve human cell types reveals an intermediate chromatin subtype

2020-07-24

Abstract excerpt

Association of chromatin with lamin proteins at the nuclear periphery has emerged as a potential mechanism to coordinate cell type-specific gene expression and maintain cellular identity via gene silencing. Unlike many histone modifications and chromatin-associated proteins, lamin-associated domains (LADs) have yet to be mapped genome-wide in a diverse panel of human cell types, which has limited our understanding...

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Literature Corpus work: e83421ff-6bda-581c-b0b1-c33b0e1825a9
DOI: 10.1101/2020.07.23.218768

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