Article

Chromatin protein complexes involved in gene repression in lamina-associated domains

2024-05-06

Abstract excerpt

<h4>ABSTRACT</h4> Lamina-associated domains (LADs) are large chromatin regions that are associated with the nuclear lamina (NL) and form a repressive environment for transcription. The molecular players that mediate gene repression in LADs are currently unknown. Here we performed FACS-based whole-genome genetic screens in human cells using LAD-integrated fluorescent reporters to identify such regulators. Surprisi...

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Literature Corpus work: 8880f2da-0ee7-54c6-90c7-02922b28c892
DOI: 10.1101/2024.05.05.592629

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