Article

The trypanocidal benzoxaborole AN7973 inhibits trypanosome mRNA processing

2018-04-06

Abstract excerpt

Kinetoplastid parasites - trypanosomes and leishmanias - infect millions of humans and cause economically devastating diseases of livestock, and the few existing drugs have serious deficiencies. Benzoxaborole-based compounds are very promising potential novel anti-trypanosomal therapies, with candidates already in human and animal clinical trials. Their targets in trypanosomes were hitherto unknown. We investigate...

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Literature Corpus work: e7ea3286-9a04-518b-8d9f-f0d0c82361c3
DOI: 10.1101/295550

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