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Article

Targeting Toxoplasma gondii CPSF3 as a new approach to control toxoplasmosis

1 Feb 2017

Abstract excerpt

Toxoplasma gondii is an important food and waterborne pathogen causing toxoplasmosis, a potentially severe disease in immunocompromised or congenitally infected humans. Available therapeutic agents are limited by suboptimal efficacy and frequent side effects that can lead to treatment discontinuation. Here we report that the benzoxaborole AN3661 had potent in vitro activity against T. gondii. Parasites selected...

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PMID: 28148555
DOI: 10.15252/emmm.201607370

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