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Clinical and veterinary trypanocidal benzoxaboroles target CPSF3

5 Sept 2018

Abstract excerpt

African trypanosomes cause lethal and neglected tropical diseases, known as sleeping sickness in humans and nagana in animals. Current therapies are limited, but fortunately, promising therapies are in advanced clinical and veterinary development, including acoziborole (AN5568 or SCYX-7158) and AN11736, respectively. These benzoxaboroles will likely be key to the World Health Organization’s target of disease...

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Biochemical and Molecular Research
Signaling Pathways in Disease
Trypanosoma species research and implications

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 30185555
DOI: 10.1073/pnas.1807915115

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