Article

Propionate reinforces epithelial identity and reduces aggressiveness of non-small cell lung carcinoma via chromatin remodelling

2023-01-20

Abstract excerpt

Epithelial to mesenchymal transition (EMT) is a developmental cellular program driving metastasis and chemo-resistance in cancer, but its pharmacological treatment has been so far challenging. Targeting deregulated metabolic processes in cancer is emerging as a realistic therapeutic strategy. Here, we used an EMT-focussed integrative functional genomic approach and identified negative association of the short-chai...

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Identifiers and source

Literature Corpus work: e775cc91-fa52-54f8-90cf-3bb457c58d6a
DOI: 10.1101/2023.01.19.524677

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