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Article

Butyrate as a promising therapeutic target in cancer: From pathogenesis to clinic (Review)

29 Feb 2024

Abstract excerpt

Cancer is one of the leading causes of mortality worldwide. The etiology of cancer has not been fully elucidated yet, and further enhancements are necessary to optimize therapeutic efficacy. Butyrate, a short‑chain fatty acid, is generated through gut microbial fermentation of dietary fiber. Studies have unveiled the relevance of butyrate in malignant neoplasms, and a comprehensive understanding of its role in...

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PMID: 38426581
DOI: 10.3892/ijo.2024.5632

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