Article

Short chain fatty acids regulate the chromatin landscape and distinct gene expression changes in human colorectal cancer cells

2025-05-13

Abstract excerpt

Short chain fatty acids (SCFAs) are small metabolites that are produced through the activity of microbes and have important roles in human physiology. These metabolites have varied mechanisms in interacting with the host, of which one such mode is decorating the chromatin landscape. We previously detected specific histone modifications in the mouse gut that can be derived from SCFAs and are regulated by the microb...

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Literature Corpus work: fce49311-b5b0-5e55-9ccb-dcdefc1edd29
DOI: 10.1101/2025.05.07.652677

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