Article

From transcriptomics to metabolomics: Extracellular ATP induces TGF-β-like and TGF-β-independent epithelial mesenchymal transition in lung cancer cells

2021-04-09

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold>: Epithelial mesenchymal transition (EMT) is an early process in metastasis. Extracellular ATP (eATP) was shown to play important roles in EMT. However, the mechanisms by which eATP induces EMT and ATP’s relationship to TGF-b, a well-known EMT inducer, are unclear. Key questions include: if and how much EMT-specific gene expression eATP induces and how similar is...

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Literature Corpus work: f205ce7b-8357-534f-9077-f6ec49bb4653
DOI: 10.21203/rs.3.rs-403352/v1

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