Article

Microglia are not necessary for maintenance of blood-brain barrier properties in health, but PLX5622 alters brain endothelial cholesterol metabolism

2024-02-22

Abstract excerpt

<h4>Summary</h4> Microglia are resident immune cells of the central nervous system, yet their functions far exceed those related to immunology. From pruning neural synapses during development to preventing excessive neural activity throughout life, microglia are intimately involved in the brain’s most basic processes. Studies have reported a close interaction between microglia and endothelial cells, as well as bo...

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Literature Corpus work: e74ea715-b4bc-5f3e-aac2-bfe3932a7d26
DOI: 10.1101/2024.02.20.580754

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