Article

Subventricular zone/white matter microglia reconstitute the empty adult microglial niche in a dynamic wave

2021-02-18

Abstract excerpt

Microglia, the brain’s resident myeloid cells, play central roles in brain defense, homeostasis, and disease. Using sustained colony-stimulating factor 1 receptor inhibition, we report an unprecedented level of microglial depletion and establish a model system that achieves an empty microglial niche in the adult brain. We identify a myeloid cell that migrates from an important neurogenic niche, the subventricular...

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Literature Corpus work: d4683111-624c-5585-a499-edef1963c0c7
DOI: 10.1101/2021.02.17.431594

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