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Endocannabinoid Modulation of Microglial Phenotypes in Neuropathology

14 Feb 2020

Abstract excerpt

Microglia, the resident immune cells of the central nervous system, mediate brain homeostasis by controlling neuronal proliferation/differentiation and synaptic activity. In response to external signals from neuropathological conditions, homeostatic (M0) microglia can adopt one of two activation states: the classical (M1) activation state, which secretes mediators of the proinflammatory response, and the...

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PMID: 32117037
DOI: 10.3389/fneur.2020.00087

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