Article
Microglia phenotype diversity.
CNS & neurological disorders drug targets - 1 Feb 2011
Olah M, Biber K, Vinet J, Boddeke H W G M
Abstract excerpt
Microglia, the tissue macrophages of the brain, have under healthy conditions a resting phenotype that is characterized by a ramified morphology. With their fine processes microglia are continuously scanning their environment. Upon any homeostatic disturbance microglia rapidly change their phenotype and contribute to processes including inflammation, tissue remodeling, and neurogenesis. In this review, we will...
Topics
- Aging
- Brain
- Brain Neoplasms
- Cells, Cultured
- Humans
- Inflammation
- Microglia
- Neurogenesis
- Phenotype