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Novel adenoma-immune phenotypes are associated with risk of metachronous polyps and colorectal cancer in a bowel screening cohort

2026-02-27

Abstract excerpt

<h4>Background</h4> Current British Society of Gastroenterology (BSG) guidelines misclassify metachronous lesion risk after polypectomy in approximately 40% of patients. Building on evidence that immune exclusion drives progression of adenomas to colorectal cancer, this study examined immune profiles in screen-detected adenomas as a predictive biomarker for metachronous lesion risk. <h4>Methods</h4> Patients und...

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Literature Corpus work
e71b0c26-2b5b-5fc8-b5d7-95e1fad46f3a
DOI
10.64898/2026.02.25.26346992
Open publication

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