Article

Continuous Genetic Recording with Self-Targeting CRISPR-Cas in Human Cells

2016-05-20

Abstract excerpt

The ability to longitudinally track and record molecular events in vivo would provide a unique opportunity to monitor signaling dynamics within cellular niches and to identify critical factors in orchestrating cellular behavior. We present a self-contained analog memory device that enables the recording of molecular stimuli in the form of DNA mutations in human cells. The memory unit consists of a self-targeting...

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Literature Corpus work: e6d5dc70-4ee2-5736-a9db-8c3416b69b83
DOI: 10.1101/053058

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