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DNA writing at a single genomic site enables lineage tracing and analog recording in mammalian cells

2019-05-16

Abstract excerpt

<h4>Summary</h4> The study of intricate cellular and developmental processes in the context of complex multicellular organisms is difficult because it can require the non-destructive observation of thousands, millions, or even billions of cells deep within an animal. To address this difficulty, several groups have recently reported CRISPR-based DNA recorders that convert transient cellular experiences and process...

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Literature Corpus work
057092cc-cb8a-57f6-b389-f6d9eb8357b6
DOI
10.1101/639120
Open publication

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DNA writing at a single genomic site enables lineage tracing and analog recording in mammalian cellsDOI 10.1101/639120
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