Article

Synthetic gene circuits enable systems-level biosensor discovery at the host-microbe interface

2019-02-22

Abstract excerpt

<h4>ABSTRACT</h4> The composition and function of the gut microbiota are strongly associated with human health, and dysbiosis is linked to an array of diseases, ranging from obesity and diabetes to infection and inflammation. Engineering synthetic circuits into gut bacteria to sense, record and respond to in vivo signals is a promising new approach for the diagnosis, treatment and prevention of disease. Here, we...

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Literature Corpus work: 665493e0-9bc9-5507-8c09-3cf329d956ed
DOI: 10.1101/557934

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