Article

Sensing endogenous RNA in living human cells using a CRISPR-activated protease

2024-07-18

Abstract excerpt

<h4>ABSTRACT</h4> Most techniques used to detect specific mRNAs in eukaryotic cells require to extract nucleic acids and thereby kill the cells. A programmable sensor for monitoring endogenous transcripts in living cells, in contrast, would enable to enrich living cells based on a specific transcription or splicing event, and studying these cells by live microscopy or sequencing methods requiring intact cells. We...

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Literature Corpus work: ccc9c9fe-dbc9-5ba4-89aa-7e7aee748d22
DOI: 10.1101/2024.07.17.603943

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