Article
Engineered bacteria detect tumor DNA
2021-09-11
Abstract excerpt
<h4>Summary</h4> Advances in bacterial engineering have catalysed the development of living cell diagnostics and therapeutics 1–3 , including microbes that respond to gut inflammation 4 , intestinal bleeding 5 , pathogens 6 and hypoxic tumors 7 . Bacteria can access the entire gastrointestinal tract 8 to produce outputs measured in stool 4 or urine 7 . Cellular memory, such as bistable switches 4,9,10 or...
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Identifiers and source
- Literature Corpus work
- 7f45d005-cbc6-5c37-b2dd-c19b9ce4fa16
- DOI
- 10.1101/2021.09.10.459858