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Article

Physical theory of epigenetic memory and its biological implications

2026-04-10

Abstract excerpt

Epigenetic marks are essential for maintaining cell identity, yet how epigenetic memory is robustly preserved across cell cycles while remaining plastic during cell-state transitions remains unclear. Here, we develop a theory of epigenetic memory that incorporates chromatin compartmentalization and mark modifications, including long-range spreading, writing, and erasing. The spreading-writing-erasing model generat...

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Literature Corpus work
e6d25966-d58b-5d33-9199-98dd558113ff
DOI
10.64898/2026.04.08.717143
Open publication

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Physical theory of epigenetic memory and its biological implicationsDOI 10.64898/2026.04.08.717143
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