Article

Astrocyte morphogenesis requires self-recognition

2024-02-22

Abstract excerpt

<title>Abstract</title> <p>Self-recognition is a fundamental cellular process across evolution and forms the basis of neuronal self-avoidance1-4. Clustered protocadherins (Pcdh), comprising a large family of isoform-specific homophilic recognition molecules, play a pivotal role in neuronal self-avoidance required for mammalian brain development5-7. The probabilistic expression of different Pcdh isoforms confers u...

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Literature Corpus work: e6b084d4-0fef-5131-99d3-62b73aaed6f9
DOI: 10.21203/rs.3.rs-3932947/v1

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