Article

Clustered γ-Protocadherins Regulate Cortical Interneuron Programmed Cell Death

2020-01-15

Abstract excerpt

Cortical function critically depends on inhibitory/excitatory balance. GABAergic cortical inhibitory interneurons (cINs) are born in the ventral forebrain. After completing their migration into cortex, their final numbers are adjusted-during a period of postnatal development - by programmed cell death (PCD). The mechanisms that regulate cIN elimination remain controversial. Here we show that genes in the protocadh...

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Literature Corpus work: 896400d9-7335-5024-bc31-f674cefaff3a
DOI: 10.1101/2020.01.14.906941

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