Article

Protocadherin γC4 regulates neuronal survival and dendritic self-avoidance

2025-06-04

Abstract excerpt

<title>Abstract</title> <p>Animal models of human disease syndromes are useful for elucidating disease causes and developing treatments. The protocadherin γC4 (Pcdh-γC4) among the 22 isoforms encoded by the protocadherin-γ (Pcdh-γ) gene cluster causes a human neurodevelopmental syndrome with progressive microcephaly, seizures, and intellectual disorder. Here, we successfully established a useful mouse model of hu...

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Literature Corpus work: 9bfa8b26-5ec9-58b6-978b-cab77691cef9
DOI: 10.21203/rs.3.rs-6625601/v1

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