Article
Control of CNS synapse development by {gamma}-protocadherin-mediated astrocyte-neuron contact.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 23 Sept 2009
Garrett Andrew M, Weiner Joshua A
Abstract excerpt
Recent studies indicate that astrocytes, whose processes enwrap synaptic terminals, promote synapse formation both by releasing soluble factors and through contact-dependent mechanisms. Although astrocyte-secreted synaptogenic factors have been identified, the molecules underlying perisynaptic astroctye-neuron contacts are unknown. Here we show that the gamma-protocadherins (gamma-Pcdhs), a family of 22 neuronal...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
