Article

Village in a dish: a model system for population-scale hiPSC studies

2021-08-19

Abstract excerpt

The mechanisms by which DNA alleles contribute to disease risk, drug response, and other human phenotypes are highly context-specific, varying across cell types and under different conditions. Human induced pluripotent stem cells (hiPSCs) are uniquely suited to study these context-dependent effects, but to do so requires cell lines from hundreds or potentially thousands of individuals. Village cultures, where mult...

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Literature Corpus work: e67c3032-c810-5ecd-8409-13c56067b990
DOI: 10.1101/2021.08.19.457030

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