Diversity in a dish: Leveraging organoids to reflect genetic ancestry and sex differences in health and disease

Abstract excerpt

The interplay between genetic ancestry and biological sex is increasingly recognized as a critical factor influencing health outcomes, treatment efficacy, and drug toxicity . Current research highlights significant disparities in disease susceptibility and therapeutic responses across different ancestral groups and sexes, with underrepresentation of diverse populations in genomic studies impeding progress. Most Ge...

Topics

Open a Topic to create a Post that cites this publication.

• Nutrition, Genetics, and Disease
• Race, Genetics, and Society
• Sex and Gender in Healthcare

Identifiers and source

Literature Corpus work

b89178fe-05b7-5812-af94-1241df6b9e76

DOI

10.1016/j.cobme.2025.100592