Article
Humanity in a Dish: Population Genetics with iPSCs.
Trends in cell biology - 1 Jan 2018
Warren Curtis R, Cowan Chad A
Abstract excerpt
Induced pluripotent stem cells (iPSCs) are powerful tools for investigating the relationship between genotype and phenotype. Recent publications have described iPSC cohort studies of common genetic variants and their effects on gene expression and cellular phenotypes. These in vitro quantitative trait locus (QTL) studies are the first experiments in a new paradigm with great potential: iPSC-based functional...
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