Article

Identification of molecular determinants governing KIF4 cargo recognition of NTCP and their role in HBV/HDV infection

2026-02-26

Abstract excerpt

The surface availability of the sodium taurocholate co-transporting polypeptide (NTCP), which serves as entry receptor for Hepatitis B virus (HBV) and Hepatitis D virus (HDV), is a key determinant of HBV/HDV infectivity. We previously identified the Kinesin motor protein KIF4 as a key regulator of NTCP trafficking to the plasma membrane. However, the molecular mechanism by which NTCP is recognized as a KIF4 transp...

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Literature Corpus work: e5c0c6ba-bf14-5efb-92af-f2185be8eafd
DOI: 10.64898/2026.02.26.708216

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