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Article

A protein kinase CK2 site flanking the nuclear targeting signal enhances nuclear transport of human cytomegalovirus ppUL44.

Traffic (Copenhagen, Denmark) - 1 Nov 2005

Alvisi Gualtiero, Jans David A, Guo Jinjin, Pinna Lorenzo A, Ripalti Alessandro

Abstract excerpt

The processivity factor of the human cytomegalovirus (HCMV) DNA polymerase phosphoprotein ppUL44 plays an essential role in viral replication, showing nuclear localization in infected cells. The present study examines ppUL44's nuclear import pathway for the first time, ectopic expression of ppUL44 revealing a strong nuclear localization in transfected COS-7 and other cell types, implying that no other HCMV...

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Identifiers

PMID: 16190981
DOI: 10.1111/j.1600-0854.2005.00331.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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