Article

Decoding the transcriptome of atherosclerotic plaque at single-cell resolution

2020-03-04

Abstract excerpt

Atherogenesis involves an interplay of inflammation, tissue remodeling and cellular transdifferentiation (CTD), making it especially difficult to precisely delineate its pathophysiology. Here we examine the single-cell transcriptome of entire atherosclerotic core (AC) plaques and patient-matched proximal adjacent (PA) portions of carotid artery tissue from patients undergoing carotid endarterectomy. We use a novel...

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Literature Corpus work: e5beaf38-bfcf-56ec-8566-0f0065acfc1b
DOI: 10.1101/2020.03.03.968123

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