Article

Distinct sequencing success at non-B-DNA motifs

2022-06-16

Abstract excerpt

Modern sequencing technologies are not error-free, and might have elevated error rates at some locations of the genome. A potential cause for such elevated error rates is the formation of alternative DNA structures (non-B DNA), such as G-quadruplexes (G4s), Z-DNA, or cruciform structures, during sequencing. Approximately 13% of the human genome has the potential to form such structures, which have been previously...

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Literature Corpus work: e5ae750a-b10c-595b-bc23-34b749ba8a82
DOI: 10.1101/2022.06.13.495922

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