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Patient iPSC models reveal glia-intrinsic phenotypes in multiple sclerosis

2023-08-02

Abstract excerpt

<h4>Summary</h4> Multiple sclerosis (MS) is considered an inflammatory and neurodegenerative disease of the central nervous system, typically resulting in significant neurological disability that worsens over time. While considerable progress has been made in defining the immune system’s role in MS pathophysiology, the contribution of intrinsic CNS-cell dysfunction remains unclear. Here, we generated the largest...

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Literature Corpus work
e5a5f895-63f6-5beb-8180-87ff62283457
DOI
10.1101/2023.08.01.551553
Open publication

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Patient iPSC models reveal glia-intrinsic phenotypes in multiple sclerosisDOI 10.1101/2023.08.01.551553
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