Article

Single-cell analysis suggests coordinated immune-cell redistribution between blood and cerebrospinal fluid in early multiple sclerosis

2026-08-09

Abstract excerpt

Despite immune-cell infiltration being a hallmark of multiple sclerosis (MS), the interplay between the periphery and central nervous system immune responses is still incompletely characterized. We performed single-cell transcriptomic and V(D)J sequencing of paired blood and cerebrospinal fluid (CSF) immune cells from treatment-naive relapsing-remitting women with MS and compared them to age– and sex-matched healt...

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Literature Corpus work: 1ab4a9bb-f408-532b-b049-09bbe4a5048c
DOI: 10.64898/2026.08.04.742373

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