Article

High-dimensional causal mediation analysis by partial sum statistic and sample splitting strategy in imaging genetics application

2024-06-24

Abstract excerpt

Causal mediation analysis provides a systematic approach to explore the causal role of one or more mediators in the association between exposure and outcome. In omics or imaging data analysis, mediators are often high-dimensional, which brings new statistical challenges. Existing methods either violate causal assumptions or fail in interpretable variable selection. Additionally, mediators are often highly correlat...

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Literature Corpus work: e5584f51-a80c-52f4-8478-b6d5c2caf0c3
DOI: 10.1101/2024.06.23.24309362

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