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Adipocyte-specific ablation of the Ca <sup>2+</sup> pump SERCA2 impairs whole-body metabolic function and reveals the diverse metabolic flexibility of white and brown adipose tissue

2022-03-12

Abstract excerpt

<h4>Objective</h4> Sarco/endoplasmic reticulum Ca 2+ -ATPase (SERCA) transports Ca 2+ from the cytosol into the ER and is essential for appropriate regulation of intracellular Ca 2+ homeostasis. The objective of this study was to test the hypothesis that SERCA pumps are involved in the regulation of white adipocyte hormone secretion and other aspects of adipose tissue function and that this control is disturbe...

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Literature Corpus work
e44ce413-467b-5c6f-abf9-b1b754cff168
DOI
10.1101/2022.03.11.483886
Open publication

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Adipocyte-specific ablation of the Ca <sup>2+</sup> pump SERCA2 impairs whole-body metabolic function and reveals the diverse metabolic flexibility of white and brown adipose tissueDOI 10.1101/2022.03.11.483886
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