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Calcium signalling and ER stress in insulin resistance and atherosclerosis

14 Oct 2016

Abstract excerpt

The burden of type 2 diabetes and its major complication cardiovascular disease is rapidly increasing worldwide. Understanding the underlying pathogenic mechanisms of these diseases is crucial to develop novel therapeutics. Recent work using genetic and biochemical methods in mouse models and human samples have identified disturbed calcium signalling and endoplasmic reticulum stress as emerging factors involved...

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PMID: 27739133
DOI: 10.1111/joim.12562

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