Article

A Data-Analysis Pipeline for High-Throughput Systematic Evolution of Ligands by Exponential Enrichment (HT-SELEX) in the Characterization of Telomeric Proteins

2026-03-07

Abstract excerpt

<h4>ABSTRACT</h4> Telomeres are nucleoprotein structures at the ends of eukaryotic chromosomes that safeguard them from triggering inappropriate DNA damage signaling. POT1, a member of the mammalian shelterin complex, binds single-stranded (ss) telomeric DNA and blocks the activation of the ATR kinase-mediated DNA damage response at telomeres. Yet until recently, it was poorly understood how the double-stranded (...

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Literature Corpus work: e4447c9c-8d9d-578c-80c4-dfaeff930ca3
DOI: 10.64898/2026.03.06.710105

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