Article

The double-stranded DNA-binding proteins TEBP-1 and TEBP-2 form a telomeric complex with POT-1

2020-08-19

Abstract excerpt

Telomeres are bound by dedicated protein complexes, like shelterin in mammals, which protect telomeres from DNA damage. In the nematode Caenorhabditis elegans , a comprehensive understanding of the proteins interacting with the telomere sequence is lacking. Here, we harnessed a quantitative proteomics approach to screen for proteins binding to C. elegans telomeres , and identified TEBP-1 and TEBP-2, two paralogs...

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Literature Corpus work: c9f4bc31-7551-52cd-b6dc-8941a9ee958f
DOI: 10.1101/2020.08.19.256388

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