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Article

The double-stranded DNA-binding proteins TEBP-1 and TEBP-2 form a telomeric complex with POT-1.

Nature communications - 11 May 2021

Dietz Sabrina, Almeida Miguel Vasconcelos, Nischwitz Emily, Schreier Jan, Viceconte Nikenza, Fradera-Sola Albert, Renz Christian, Ceron-Noriega Alejandro, Ulrich Helle D, Kappei Dennis, Ketting René F, Butter Falk

Abstract excerpt

Telomeres are bound by dedicated proteins, which protect them from DNA damage and regulate telomere length homeostasis. In the nematode Caenorhabditis elegans, a comprehensive understanding of the proteins interacting with the telomere sequence is lacking. Here, we harnessed a quantitative proteomics approach to identify TEBP-1 and TEBP-2, two paralogs expressed in the germline and embryogenesis that associate to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33976151
DOI: 10.1038/s41467-021-22861-2
PMCID: PMC8113555

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The double-stranded DNA-binding proteins TEBP-1 and TEBP-2 form a telomeric complex with POT-1.PMID 33976151Read ↗

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