Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Tying up the Ends: Plasticity in the Recognition of Single-Stranded DNA at Telomeres

30 Aug 2016

Abstract excerpt

Telomeres terminate nearly exclusively in single-stranded DNA (ssDNA) overhangs comprised of the G-rich 3' end. This overhang varies widely in length from species to species, ranging from just a few bases to several hundred nucleotides. These overhangs are not merely a remnant of DNA replication but rather are the result of complex further processing. Proper management of the telomeric overhang is required both...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CRISPR and Genetic Engineering
Share to DNA Repair Mechanisms
Share to Telomeres, Telomerase, and Senescence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 27575340
DOI: 10.1021/acs.biochem.6b00496

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Tying up the Ends: Plasticity in the Recognition of Single-Stranded DNA at TelomeresPMID 27575340Read ↗

DNA self-recognition in the structure of Pot1 bound to telomeric single-stranded DNA.Semantic proximity Read ↗

Protection of telomeres by a conserved Stn1–Ten1 complexSemantic proximity Read ↗

Human POT1 protects the telomeric ds-ss DNA junction by capping the 5' end of the chromosome.Semantic proximity Read ↗

Structure of the Human Telomeric Stn1-Ten1 Capping ComplexSemantic proximity Read ↗

Fission yeast Pot1-Tpp1 protects telomeres and regulates telomere length.Semantic proximity Read ↗

How telomeric protein POT1 avoids RNA to achieve specificity for single-stranded DNASemantic proximity Read ↗

Linear chromosome maintenance in the absence of essential telomere-capping proteins.Semantic proximity Read ↗

TRF2 promotes dynamic and stepwise looping of POT1 bound telomeric overhangSemantic proximity Read ↗

Human shelterin protein POT1 prevents severe telomere instability induced by homology-directed DNA repair.Semantic proximity Read ↗

The TEL patch of telomere protein TPP1 mediates telomerase recruitment and processivity.Semantic proximity Read ↗

A Data-Analysis Pipeline for High-Throughput Systematic Evolution of Ligands by Exponential Enrichment (HT-SELEX) in the Characterization of Telomeric ProteinsSemantic proximity Read ↗

Distinct functions of POT1 proteins contribute to the regulation of telomerase recruitment to telomeresSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.