Article

Inhibitory KIR ligands are associated with higher<i>P. falciparum</i>parasite prevalence

2020-04-07

Abstract excerpt

Killer cell immunoglobulin-like receptors (KIR) and their HLA ligands influence the outcome of many infectious diseases. We analyzed the relationship of compound KIR-HLA genotypes with risk of Plasmodium falciparum infection in a longitudinal cohort of 890 Ugandan individuals. We found that presence of HLA-C2 and HLA-Bw4, ligands for inhibitory KIR2DL1 and KIR3DL1, respectively, increased the likelihood of P. falc...

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Literature Corpus work: e43e5c43-0181-557d-aeac-61877c89ddbf
DOI: 10.1101/2020.04.04.20053504

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