Article
Killer cell immunoglobulin-like receptor (KIR) genes and their HLA-C ligands in a Ugandan population.
Immunogenetics - 1 Nov 2013
Nakimuli Annettee, Chazara Olympe, Farrell Lydia, Hiby Susan E, Tukwasibwe Stephen, Knee Olatejumoye, Jayaraman Jyothi, Traherne James A, Elliott Alison M, Kaleebu Pontiano, Mirembe Florence, Moffett Ashley
Abstract excerpt
Killer cell immunoglobulin-like receptor (KIR) genes are expressed by natural killer cells and encoded by a family of genes exhibiting considerable haplotypic and allelic variation. HLA-C molecules, the dominant ligands for KIR, are present in all individuals and are discriminated by two KIR epitopes, C1 and C2. We studied the frequencies of KIR genes and HLA-C1 and C2 groups in a large cohort (n = 492) from...
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