Article
Killer-cell immunoglobulin-like receptors and malaria caused by Plasmodium falciparum in The Gambia.
Tissue antigens - 1 Feb 2012
Yindom L-M, Forbes R, Aka P, Janha O, Jeffries D, Jallow M, Conway D J, Walther M
Abstract excerpt
The relevance of innate immune responses to Plasmodium falciparum infection, in particular the central role of natural killer (NK) cell-derived interferon gamma (IFN-γ), is becoming increasingly recognised. Recently, it has been shown that IFN-γ production in response to P. falciparum antigens is in part regulated by killer-cell immunoglobulin-like receptor (KIR) genes, and a study from malaria-exposed...
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