Article
Differential association of gene content polymorphisms of killer cell immunoglobulin-like receptors with placental malaria in HIV- and HIV+ mothers.
PloS one - 1 Jan 2012
Omosun Yusuf O, Blackstock Anna J, Gatei Wangeci, Hightower Allen, van Eijk Anne Maria, Ayisi John, Otieno Juliana, Lal Renu B, Steketee Richard, Nahlen Bernard, ter Kuile Feiko O, Slutsker Laurence, Shi Ya Ping
Abstract excerpt
Pregnant women have abundant natural killer (NK) cells in their placenta, and NK cell function is regulated by polymorphisms of killer cell immunoglobulin-like receptors (KIRs). Previous studies report different roles of NK cells in the immune responses to placental malaria (PM) and human immunodeficiency virus (HIV-1) infections. Given these references, the aim of this study was to determine the association...
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