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Article

HLA Alleles B53:01 and C06:02 Are Associated With Higher Risk of P. falciparum Parasitemia in a Cohort in Uganda.

Frontiers in immunology - 1 Jan 2021

Digitale Jean C, Callaway Perri C, Martin Maureen, Nelson George, Viard Mathias, Rek John, Arinaitwe Emmanuel, Dorsey Grant, Kamya Moses, Carrington Mary, Rodriguez-Barraquer Isabel, Feeney Margaret E

Abstract excerpt

Variation within the HLA locus been shown to play an important role in the susceptibility to and outcomes of numerous infections, but its influence on immunity to P. falciparum malaria is unclear. Increasing evidence indicates that acquired immunity to P. falciparum is mediated in part by the cellular immune response, including NK cells, CD4 and CD8 T cells, and semi-invariant γδ T cells. HLA molecules expressed...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 33815410
DOI: 10.3389/fimmu.2021.650028
PMCID: PMC8017319

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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