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Decoding polyubiquitin regulation of K <sub>V</sub> 7. 1 functional expression with engineered linkage-selective deubiquitinases

2024-09-17

Abstract excerpt

Protein posttranslational modification with distinct polyubiquitin linkage chains is a critical component of the ‘ubiquitin code’ that universally regulates protein expression and function to control biology. Functional consequences of diverse polyubiquitin linkages on proteins are mostly unknown, with progress hindered by a lack of methods to specifically tune polyubiquitin linkages on individual proteins in live...

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Literature Corpus work
e41398f8-1807-5483-8344-799988ff3c97
DOI
10.1101/2024.09.17.613539
Open publication

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Decoding polyubiquitin regulation of K <sub>V</sub> 7. 1 functional expression with engineered linkage-selective deubiquitinasesDOI 10.1101/2024.09.17.613539
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