Article

Comparative Performance of Polygenic Risk Scores for Atherosclerotic Cardiovascular Disease Subtypes in the<i>All of Us</i>Research Program

2024-11-05

Abstract excerpt

<h4>Background</h4> Performance and portability of contemporary polygenic risk scores (PRS) for atherosclerotic cardiovascular disease (ASCVD) phenotypes vary based on different methods, training data, and trait ascertainment. <h4>Objectives</h4> We aimed to investigate performance and portability of contemporary PRS for ASCVD subtypes: coronary heart disease (CHD), abdominal aortic aneurysm (AAA), ischemic stroke...

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Literature Corpus work: e3f4f920-f87f-5e56-a13e-ad025213b9fd
DOI: 10.1101/2024.11.05.24316750

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