Article

Myeloid HIF-1α Sustains Hypoxic Fibrotic Fronts and Drives Pulmonary Fibrosis

2026-03-11

Abstract excerpt

<h4>Rationale</h4> Progressive fibrosing interstitial lung disease features “advancing fronts” where new matrix is deposited, but the signals sustaining these propagating niches remain incompletely defined. <h4>Objectives</h4> To determine the spatial and temporal compartments in which HIF-1α operates during fibrotic progression and to test whether myeloid HIF-1α is a tractable driver of lesion propagation. <h4>...

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Literature Corpus work: e3ac4ad6-ae76-5025-a686-64b0e3dac875
DOI: 10.64898/2026.03.09.710578

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